Dr. Robert Green: A liberating vision of the future
The G Word |
October 2021
Podcast
“We have a wild card here that is changing the risk-benefit equation for all babies in order to detect these rare cases.”
Using genomics in medicine
Return of individual research results from genomic research: A systematic review of stakeholder perspectives
PLOS One
In Press
Diverse Boston neighborhoods recruited for sweeping study of genetics and health outcomes
GBH News |
September 2021
Press, Radio
“Medical researchers in Boston are helping sign up one million volunteers for a first-of-its-kind study [The All of Us Research Program] examining the link between genes and our health. Researchers are actively recruiting volunteers of different races and ethnicities to ensure that the study reflects the diversity of the United States.”
Disclosing APOE genotype to individuals at risk for Alzheimer’s disease
Alzheimer's Disease International
September 2021
Using the Alzheimer’s Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer’s disease
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
September 2021
Sequencing every newborn’s genome to detect diseases faces ethical and practical obstacles, but the United Kingdom is pushing ahead with a major test
Science |
September 2021
Press
Genomic testing for Baby Cora, a participant of The BabySeq Project, revealed a disorder that might otherwise have gone undetected through traditional newborn screening. “Cora’s case illustrates the promise of sequencing the entire genomes of newborns: uncovering a bounty of genetic information that could identify infants needing treatment and improve health later in life…Genomics England … Continued
Low frequency of treatable pediatric disease alleles in gnomAD: An opportunity for future genomic screening of newborns
Human Genetics and Genomics
September 2021
Returning actionable genomic results in a research biobank: Analytic validity, clinical implementation and resource utilization
American Journal of Human Genetics
In Press
Re-evaluating the “right not to know” in genomics research
Genetics in Medicine
In Press
Study finds genomic sequencing of healthy newborns does not disrupt family dynamics
EurekAlert |
August 2021
Press, Press Release
“We have now shown that this information can be medically beneficial through early intervention and is not disruptive to the parent-infant relationship, and our ongoing analysis is measuring economic effects of genome sequencing. This type of research is critical to determine best practices for preventive genomic healthcare throughout the lifespan.” – Robert Green
Determining family impact of genome sequencing on newborns
Health IT Analytics |
August 2021
Press
“Researchers examined how conducting genome sequencing on newborns can impact family dynamics.”
Can parents handle finding out their newborn is at higher risk of certain diseases? A small study suggests they can
STAT |
August 2021
Press
“When parents were surveyed about measures like how well they bonded with their children, their levels of distress, and even the parents’ relationships with one another, there were no meaningful differences for parents whose children had their genomes sequenced compared to those whose children underwent standard newborn screening.”
Sequencing of newborns does not create negative psychosocial effect on families, study finds
Genome Web |
August 2021
Press
“Researchers studying the psychosocial effect of newborn genomic sequencing on families in the BabySeq project have found that there was no persistent negative psychosocial harm in families who received such sequencing, nor among those who received a monogenic disease risk finding for their infants.”
Green receives NIH research grant for BabySeq2
Brigham Publications: Awards, Honors & Grants |
August 2021
Press
“Robert Green, MD, MPH, of the Division of Genetics, received a research grant from the National Institutes of Health (NIH) to fund The BabySeq Project: Phase II, also known as BabySeq2, the continuation of a project to study genome sequencing in newborns.”
Improved provider preparedness through an eight-part genetics and genomic education program
Genetics in Medicine
In Press
Controversy flares over informing research subjects about ‘incidental’ genetic findings
American Association for the Advancement of Science |
August 2021
Press
“Should people who volunteer for genomic studies be told about unrelated disease mutations that turn up in their sequence data?”
G2P Newsletter July 2021
July 2021
G2P News
Our G2P research team continues to be extraordinarily productive, publishing 21 scientific papers so far this year. This summer newsletter highlights a few of these papers, as well as G2P media features, blog posts, and policy recommendations.
Behavioral and psychological impact of genome sequencing: A pilot randomized trial of primary care and cardiology patients
npj Genomic Medicine
August 2021
Robert Green: Newborn sequencing is the goal here in the U.S.
Mendelspod |
July 2021
Podcast
“If you go to a scientific meeting, even with the greatest critics, and you ask, how many people in this audience believe that your entire genome will be part of your everyday medical care in fifty years, every person will raise their hand. So the only questions we’re debating are: how do we get there, … Continued
Unlocking the human genetics of COVID
Medium |
July 2021
G2P Blog
In an unprecedented international effort, researchers and clinicians tackle the genomics of COVID-19 risk. In this blog post, G2P Director Robert Green writes about what we’ve learned so far concerning genetics and COVID-19 and how the G2P research program has contributed to these growing studies.
How will Aducanumab approval impact Alzheimer’s disease research?
Journal of Prevention of Alzheimer's Disease
July 2021
The role of SLCO1B1 genotyping in lowering cardiovascular risk
Pharmacogenomics
July 2021
Effects of participation in a U.S. trial of newborn genomic sequencing on parents at risk for depression
Journal of Genetic Counseling
July 2021
An international policy on returning genomic research results
Genome Medicine
July 2021
Polygenic risk scores in the clinic: Translating risk into action
Human Genetics and Genomics
July 2021
Molecular cancer screening: In search of evidence
Nature Medicine
July 2021
Development and validation of a comprehensive genomics knowledge scale
Public Health Genomics
May 2021
Precision medicine: From breakthrough to follow-through
Medium |
May 2021
G2P Blog
Nic Encina, Director of Strategy of the Precision Population Health (PPH) Initiative at Ariadne Labs, describes the recent launch of PPH into the world of precision medicine. “We feel that Genomes2People’s real-world research in genomic return-of-results combined with Ariadne Labs’ practical approach to health system innovation and implementation are aptly suited for tackling implementation obstacles … Continued
A framework for automated gene selection in genomic sequencing
Genetics in Medicine
June 2021
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection
Nature Medicine
June 2021
Primary care providers’ responses to unsolicited Lynch syndrome secondary findings of varying clinical significance
Genetics in Medicine
June 2021
Precision Pioneers EP 4: Geneticist and Harvard professor, Robert Green on accelerating implementation of genomic medicine
The Genetics Podcast |
April 2021
Podcast
Dr. Robert C. Green joins Patrick Short of “The Genetics Podcast” to discuss genetic testing in healthy adults and newborns, along with the barriers we need to overcome to realize the full potential of personalized medicine.
Psychosocial effect of newborn genomic sequencing on families in the BabySeq Project
JAMA Pediatrics
August 2021
Precision Population Health initiative targets precision medicine delivery in primary care
Healthcare Innovation |
March 2021
Press
Joint project between Ariadne Labs and Genomes2People to create implementation pathways, tools and guides that work across various clinical contexts.
Ariadne Labs and Genomes2People launch new Precision Population Health initiative
PR Newswire |
March 2021
Press Release
The Precision Population Health (PPH) initiative, a collaboration between Genomes2People and Ariadne Labs, aims to solve the system challenges in adopting precision medicine in primary care, and bring about a promising, equitable approach to medicine for every patient, everywhere. Our vision is not to simply introduce new tools to primary care, but rather to transform … Continued
Combining science and service as a VA genetic counselor
VAntage Point |
March 2021
Press
“In 2019, [G2V’s] Morgan Danowski graduated and joined Boston VA. There, she supports VA’s Million Veteran Program (MVP), now the world’s largest genomics research program. The program takes DNA from participating Veterans and information on their health, lifestyle and military experiences and exposures to better understand disease in Veteran populations. With over 830,000 Veterans enrolled, … Continued
