Using genomics in medicine
MassMutual is rolling out free genetic testing for members, a dicey area for life insurers
MassMutual announced Tuesday that it’s offering many of its 4.2 million policyholders free genetic risk assessments for eight common diseases, like heart disease, type 2 diabetes, and breast cancer. “I think what’s remarkable about this story is that in some ways it’s taken so long,’’ said Robert Green, a medical geneticist and professor at Harvard … Continued
Managing differential performance of polygenic risk scores across groups: real-world experience of the eMERGE Network
Interview: Nina Gold
In this interview with the European Medical Journal, Dr. Nina Gold reflects on what inspired her career in pediatric genetics. She describes her work in clinical and research settings, particularly in the context of newborn genomic screening.
G2P March Newsletter 2024
Genomes2People’s first newsletter of 2024 highlights presentations at the ACMG Annual Clinical Genetics Meeting from several G2P collaborators including Ilham Abbasi, Dr. Nina Gold, and Dr. Kurt Christensen. The piece also highlights Dr. Robert Green’s recent interview with CBS News on Rare Disease Day that showcases findings and stories from the BabySeq Project. The newsletter … Continued
Model Bianca Balti Reflects on Her BRCA1 Diagnosis and Preventative Mastectomy
In this recent article from Vogue, top Italian model Bianca Balti shares her story of finding out that she carries the BRCA1 gene and about her choice to undergo a preventive double mastectomy. In September 2023, Bianca Balti was joined by Dr. Robert Green and Francesco Carrozzini at a Fashion4Development (F4D) event where they were … Continued
We’re identical twins who married another set of identical twins. Our babies are biological siblings
Dr. Robert Green comments on this story from TODAY about identical twins married to another set of identical twins. “Even though [the children] have different parents, they’re genetically full siblings,” says Dr. Robert Green.
A Tribute to Franca Sozzani: Celebrating FiveYears of the Franca Sozzani Fund for Preventive Genomics
Pakhi Dixit, who manages social media for Genomes2People, writes a tribute to Franca Sozzani in the latest G2P blog. She highlights Franca’s powerful legacy and story behind the Franca Sozzani Fund for Preventive Genomics which was created to, “leverage evidence and advocacy around preventive genomics so that everyone, regardless of ethnicity or socioeconomic background, may … Continued
Development and utility of a clinical research informatics application for participant recruitment and workflow management for a return of results pilot trial in familial hypercholesterolemia in the Million Veteran Program
Boston doctor wants more screening for rare genetic conditions in newborn babies
This Rare Disease Day, CBS News reports on the BabySeq Project in an interview with Dr. Robert Green and family participants from the project. Dr. Green shares how he hopes the attention will lead to more screening for genetic conditions in newborn babies.
Clinical impact of preemptive pharmacogenomic testing on antiplatelet therapy in a real-world setting
Video: Boston doctor calls for more screening for genetic rare diseases in newborns
In this short video from CBS Boston, Dr. Robert Green shares findings from the BabySeq Project and makes the case for more screening of genetic diseases in newborns. Families who participated the BabySeq Project also share their stories.
Processes and outcomes from a clinical genetics e-consultation service managed by a primary care physician champion
How Genomics Could Save Your Life
In this blog post, Dr. Robert Green poses the question: “What’s holding us back from doing more with preventive genomics in medicine?” Drawing on his recent keynote talk at the Precision Medicine Network (PMNET) Forum in Riga, Latvia, Dr. Green explores near-term applications of precision medicine using genetic testing such as: newborn and childhood sequencing, … Continued
Helping patients understand multi-cancer early detection tests: a scoping review
ThinkResearch Podcast: Genomics and Healthcare
“What role can genomics play in improving healthcare? Jason Vassy, MD, MPH, MS, of Veterans Affairs (VA) Boston Healthcare System and Brigham and Women’s Hospital shares his research on how patient DNA might be used to improve healthcare and prevent disease.”
Your Baby’s Genome: The Radical Promise of Early DNA Testing
Robert Green is interviewed by Seema Kumar, Cure CEO about The Radical Promise of Early DNA Testing for human health and longevity. He shares results from the BabySeq Project and progress on building the new start-up company, Nurture Genomics.
Genetics in the Workplace
Robert Green joins Jared Bowcutt and Adam Compton on the Brown & Brown Benefits Breakdown podcast to discuss genetics in the workplace. “Until recently, genomics has been fragmented and expensive – it has now evolved to be offered to employees and their families. Explore what you can do as an employer to make better decisions … Continued
Ready or not, genomic screening of fetuses is already here
G2P December Newsletter 2023
G2P’s final newsletter of 2023 celebrates the five year anniversary of The Franca Sozzani Fund for Preventive Genomics. Other highlights include the second annual meeting of the International Consortium on Newborn Sequencing (ICoNS) in London and the 2023 Advisory Board members of the year, Mike and Ann Marie Einziger. We also join Genomes2Veterans in celebrating … Continued
Look Who’s Talking: Research Predictions for 2024
Robert C. Green joins experts from Brigham and Women’s Hospital in sharing his 2024 predictions for scientific breakthroughs than will revolutionize research.
BabySeq, ICoNS and the power of newborn sequencing: Q&A with Dr Robert Green
“In this Q&A with Will Greene, Healthcare Engagement Lead at Roche Diagnostics Asia Pacific, Dr Green talks about his pioneering work in newborn sequencing, including via the BabySeq project and the International Consortium on Newborn Sequencing (ICoNS), as well as his broader efforts to make genomic information actionable and accessible for people everywhere.”
Broad Institute Rebrands Clinical Lab Services to Be ‘a Little Bit More Out There’
“Robert Green, a professor at Harvard Medical School and co-PI of the BabySeq2 study, said the project picked the Broad lab as its sequencing provider, while the Mass General Brigham Laboratory for Molecular Medicine (LMM) is doing the genome interpretation. The project, which is currently recruiting, intends to enroll between 500 and 2,000 families over … Continued
V.A. Recruits Millionth Veteran for Its Genetic Research Database
“On Saturday, after a 12-year effort, the Department of Veterans Affairs reached a long-term goal — it enrolled the millionth veteran in a genetic database, the Million Veteran Program. According to the V.A., the Million Veteran Program is the largest such database in the world. It includes not only genetic information but also is linked … Continued
Combined population genomic screening for three high-risk conditions in Australia: a modelling study
Newborn Sequencing 2023 Part II: What Evidence Is Enough?
Julia Karow, Managing Editor at GenomeWeb; Robert Green, Director of Genomes2People and Co-Chair of the International Consortium on Newborn Sequencing (ICoNS); Wendy Chung, Chair of Pediatrics in Medicine at Boston Children’s Hospital and leader of the Guardian Study; and James Buchanan, Senior Lecturer in Health Economics at Queen Mary University in London, discuss takeaways and … Continued
The GenoVA study: Equitable implementation of a pragmatic randomized trial of polygenic-risk scoring in primary care
Global leaders convene in London: Advancing newborn sequencing on an international scale
Earlier this month, leading researchers and experts in genomics and newborn sequencing representing the U.S., the U.K., Europe, Australia, and the Middle East came together in London at the Royal Institution for the second annual International Conference on Newborn Sequencing co-hosted with Genomics England to present updates regarding their own research and share future plans.
Five Year Follow-Up to BabySeq Project
The 2023 Precision Medicine Network (PMNET) Forum was held on October 12-13, 2023 in Riga, Latvia. PMNET’s mission is to improve patient care and outcomes by promoting development and adoption of Precision Medicine. Robert Green gave a talk about the five year follow-up of the BabySeq Project.
The Path to Universal Genomic Medicine
The 2023 Precision Medicine Network (PMNET) Forum was held on October 12-13, 2023 in Riga, Latvia. PMNET’s mission is to improve patient care and outcomes by promoting development and adoption of Precision Medicine. Robert Green shared a keynote talk during the introduction of the Forum entitled The Path to Universal Genomic Medicine.
International newborn genome sequencing projects discuss differences, future goals
Last week a dozen newborn sequencing research programs from the US, the UK, Europe, Australia, and the Middle East shared progress updates and future plans at the second annual International Conference on Newborn Sequencing (ICoNS) in London. Robert Green and Ingrid Holm, co-PIs of the BabySeq2 study, shared enrollment updates from the second iteration of … Continued
Data Sharing: A consortium-sanctioned activity to support global research and discovery
At the 2023 International Conference on Newborn Sequencing (ICoNS), Dr. David Bick; Dr. Nidhi Shah, G2P collaborator; and Rose Heald, G2P team member, share plans to share and harmonize data amongst newborn sequencing projects internationally.
BabySeq Project Update at ICoNS’23
At the 2023 International Conference on Newborn Sequencing (ICoNS), Drs. Robert Green and Ingrid Holm, Co-PIs of BabySeq2, share updates on the BabySeq Project.
ICoNS’23: Up/Downstream Ecosystem Panel
At the 2023 International Conference on Newborn Sequencing (ICoNS), Dr. Robert Green moderates a panel on the up and downstream ecosystem of newborn sequencing. Panelists include Dr. Vanessa Almendro from Danaher Corp, Dr. Paul Kruszka from GeneDx, and Dr. Jennifer Ibrahim from Sanofi.
ICoNS’23 Introduction with Drs. Robert Green and David Bick
Drs. Robert Green and David Bick, Co-Chairs of the International Consortium on Newborn Sequencing, share their introductory remarks at the start of ICoNS’23 in London, UK.
Bringing equity to genomic sequencing in newborns: BabySeq 2.0
Read about how the second iteration of The BabySeq Project, BabySeq 2.0, is striving to make genome sequencing accessible to a diverse population of newborns at Boston Children’s Hospital and other sites around the country. Ingrid Holm, MD, MPH who co-leads BabySeq 2.0 describes how seeking input from a Community Advisory Board from each participating … Continued
Fashion 4 Development Hosts the Third Annual Sustainable Goals Banquet
Fashion 4 Development (F4D) in partnership with Human Kind Institute hosted the Third Annual Sustainable Goals Banquet on Monday, September 18th during the 78th Session of the United Nations General Assembly (UNGA). The evening’s theme was ‘Healthier People, Healthier Planet.’ The night’s final award served as a tribute to the late Franca Sozzani, Editor in … Continued
G2P September Newsletter 2023
This newsletter highlights the International Conference on Newborn Sequencing (ICoNS) that is just around the corner on October 5-6, 2023 in London, UK. It’s not too late to register! Other G2P updates include media coverage of BabySeq1 publications, a new publication from the Sanford Imagenetics team about pharmacogenomics in primary care, and a blog post … Continued