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G2P Newsletter October 2021

October 2021
G2P News

This fall, we are thrilled to welcome Dr. Amy Lemke to G2P! As Executive Director of the International Newborn Screening Consortium, Dr. Lemke is taking the BabySeq Project global. She will also join the Precision Population Health (PPH) Initiative, a collaboration between G2P and Ariadne Labs. 

Internship program opens the door into the world of genetic counseling and research

Brigham Clinical and Research News |
October 2021
G2P News, Press

This year, Erin Drake, MA, director of operations for G2P, and Tala Berro, MS, CGC, a genetic counselor and project manager, helped launch the G2P BIPOC internship program in recognition of the importance of diversity not only in clinical trials but also in research teams. Research trainees Soha Mohammed, Kopika Kuhathaas and Shardae Williams share … Continued

Diverse Boston neighborhoods recruited for sweeping study of genetics and health outcomes

GBH News |
September 2021
Press, Radio

“Medical researchers in Boston are helping sign up one million volunteers for a first-of-its-kind study [The All of Us Research Program] examining the link between genes and our health. Researchers are actively recruiting volunteers of different races and ethnicities to ensure that the study reflects the diversity of the United States.”

Sequencing every newborn’s genome to detect diseases faces ethical and practical obstacles, but the United Kingdom is pushing ahead with a major test

Science |
September 2021
Press

Genomic testing for Baby Cora, a participant of The BabySeq Project, revealed a disorder that might otherwise have gone undetected through traditional newborn screening. “Cora’s case illustrates the promise of sequencing the entire genomes of newborns: uncovering a bounty of genetic information that could identify infants needing treatment and improve health later in life…Genomics England … Continued

Study finds genomic sequencing of healthy newborns does not disrupt family dynamics

EurekAlert |
August 2021
Press, Press Release

“We have now shown that this information can be medically beneficial through early intervention and is not disruptive to the parent-infant relationship, and our ongoing analysis is measuring economic effects of genome sequencing. This type of research is critical to determine best practices for preventive genomic healthcare throughout the lifespan.” – Robert Green

Green receives NIH research grant for BabySeq2

Brigham Publications: Awards, Honors & Grants |
August 2021
Press

“Robert Green, MD, MPH, of the Division of Genetics, received a research grant from the National Institutes of Health (NIH) to fund The BabySeq Project: Phase II, also known as BabySeq2, the continuation of a project to study genome sequencing in newborns.”

G2P Newsletter July 2021

July 2021
G2P News

Our G2P research team continues to be extraordinarily productive, publishing 21 scientific papers so far this year. This summer newsletter highlights a few of these papers, as well as G2P media features, blog posts, and policy recommendations.

Robert Green: Newborn sequencing is the goal here in the U.S.

Mendelspod |
July 2021
Podcast

“If you go to a scientific meeting, even with the greatest critics, and you ask, how many people in this audience believe that your entire genome will be part of your everyday medical care in fifty years, every person will raise their hand. So the only questions we’re debating are: how do we get there, … Continued

Unlocking the human genetics of COVID

Medium |
July 2021
G2P Blog

In an unprecedented international effort, researchers and clinicians tackle the genomics of COVID-19 risk. In this blog post, G2P Director Robert Green writes about what we’ve learned so far concerning genetics and COVID-19 and how the G2P research program has contributed to these growing studies.

Zara revisits iconic Peter Lindbergh photographs in a surprise collection

Vogue |
July 2021
Press

ZARA launches its first tribute collection, featuring iconic photographs by legendary image maker Peter Lindbergh. 100% of proceeds from this limited edition series curated by Fabien Baron will be donated to The Franca Sozzani Fund for Preventive Genomics, supporting the Global BabySeq Project in collaboration with Brigham and Women’s Hospital and Harvard Medical School.

The buy in

This Study Shows |
June 2021
Podcast

“We might think that science and money have nothing to do with each other, but whether it’s video games, consumer DNA kits, or even the concrete we build with, the connections are everywhere. Listen to Dr. Mitu Khandaker, Dr. John Orr, and Dr. Jason Vassy explore what happens when research and commercial interests collide.”

Precision medicine: From breakthrough to follow-through

Medium |
May 2021
G2P Blog

Nic Encina, Director of Strategy of the Precision Population Health (PPH) Initiative at Ariadne Labs, describes the recent launch of PPH into the world of precision medicine. “We feel that Genomes2People’s real-world research in genomic return-of-results combined with Ariadne Labs’ practical approach to health system innovation and implementation are aptly suited for tackling implementation obstacles … Continued

Genomic literacy in high school: Building the future

Medium |
April 2021
G2P Blog

In this blog post, G2P trainee Sachi Badola speaks to the importance of genetic literacy and proposes a genetics elective to be offered to all high school students that comprehensively covers the implications, limitations, and challenges of genomic medicine and precision health.

Ariadne Labs and Genomes2People launch new Precision Population Health initiative

PR Newswire |
March 2021
Press Release

The Precision Population Health (PPH) initiative, a collaboration between Genomes2People and Ariadne Labs, aims to solve the system challenges in adopting precision medicine in primary care, and bring about a promising, equitable approach to medicine for every patient, everywhere. Our vision is not to simply introduce new tools to primary care, but rather to transform … Continued

Combining science and service as a VA genetic counselor

VAntage Point |
March 2021
Press

“In 2019, [G2V’s] Morgan Danowski graduated and joined Boston VA. There, she supports VA’s Million Veteran Program (MVP), now the world’s largest genomics research program. The program takes DNA from participating Veterans and information on their health, lifestyle and military experiences and exposures to better understand disease in Veteran populations. With over 830,000 Veterans enrolled, … Continued

G2P Newsletter February 2021

February 2021
G2P News

Winter saw accomplishments by G2P team members through numerous projects, presentations and publications. Following the release of the NOVA documentary “Secrets in our DNA,” G2P Director Dr. Green spoke on a panel about genetics, ancestry, race and privacy issues. In December, G2P’s Carrie Blout and G2V’s Jason Vassy presented on pressing legal and policy issues … Continued

I’m 28 and I don’t know my family history – here’s how that affects my health

Well + Good |
February 2021
Press

28 year old Mercey Livingston shares about what it means to be adopted and not know important information related to family health history and genetic health. Livingston quotes G2P’s director, Dr. Robert Green, explaining the differences between direct to consumer testing and comprehensive testing options, as well as the value of working with a genetics … Continued

A pharmacist’s journey into genomic medicine

Medium |
February 2021
G2P Blog

Former G2P trainee Cathelijne van der Wouden, PharmD, shares about her journey into genomic medicine as a pharmacist-in-training in this G2P blog post.

What experts think of 23andMe’s COVID-19 risk calculator

Healthline |
February 2021
Press

In this article, Dr. Robert C. Green weighs in on 23andMe’s new interactive tool called the COVID-19 Severity Calculator. Right now the COVID-19 Severity Calculator only includes nongenetic risk factors for hospitalization from COVID-19. Dr. Green suspects that as more insights on genetic risk factors become available, 23andMe might begin incorporating genetic data into their … Continued

NOVA “Secrets in Our DNA” screening and panel discussion

Computer History Museum |
January 2021
Video

Following a screening of the NOVA documentary, “Secrets in our DNA,” the Computer History Museum hosted a panel with science and business experts about personal genetic testing. Click the link below to hear contributions by G2P director Dr. Green.

Secrets in our DNA

NOVA |
January 2021
Video

In this NOVA documentary, G2P director Dr. Green explains what DNA can reveal about our ancestry and health, and at what risk.

Latest Med News Podcast: Episode 6 with Bethany Zettler

Latest Med News |
December 2020
Podcast

In this season finale of the Latest Med News Podcast, G2P’s Bethany Zettler shares about her work as lead genetic counselor of the Preventive Genomics Clinic and project manager of the MilSeq and BabySeq studies. Her work focuses on how genetic testing can help anyone understand their health risks and make proactive medical/lifestyle choices.  

Franca Sozzani has inspired a scientific fund – And now a website

Vogue |
December 2020
Press

“Last year Sozzani’s son, the photographer and filmmaker Francesco Carrozzini, established the Franca Sozzani Fund for Preventive Genomics at Harvard University’s Brigham and Women’s Hospital with artist and investor D.A. Wallach and Genomes2People director Dr. Robert C. Green. Today marks the launch of thefrancafund.org. Its purpose is straightforward: to explain the fund’s mission, provide resources … Continued

Preventive genomics clinics: The future of precision medicine?

The Pathologist |
December 2020
Press

“Personal genetic testing is here to stay – so Bethany Zettler and Renée Pelletier recommend preventive genomics clinics as a way to offer the testing patients want without bypassing the guidance they need to fully understand their results.”

G2P Newsletter October 2020

October 2020
G2P News

Over the past few months, G2P faculty have attended numerous virtual conferences, been featured in the news and media, and contributed to studies involving the role of genetics in COVID-19. Many of our presentations are transitioning to a virtual format and shared on YouTube for all to view; make sure to check out our presentations … Continued

DNA: The next vital sign

Brigham Health |
October 2020
Press

Brigham genomics clinic makes medicine personal—and preventive.

Is aging a disease you can reverse? A look at the science behind the longevity movement

Vogue |
September 2020
Press

“Aging can be considered a disease—one that can be targeted, treated, and perhaps even reversed…The new Preventive Genomics Clinic at Brigham and Women’s Hospital in Boston is the first academic clinic in the country to offer comprehensive DNA sequencing and interpretation of nearly 6,000 disease-associated genes.”    

Genomic sequencing to screen newborns raises more false alarms than routine blood tests

STAT |
August 2020
Press

In this study led by UCSF researchers, exome sequencing was found to produce more false positives and false negatives for inherited metabolic disorders than the standard blood testing conducted in newborns. G2P’s Dr. Robert Green, co-leader of the BabySeq Project, speaks to the possibility “that the most comprehensive screening for newborns will be some combination … Continued