The BabySeq Project, funded by the NIH, is examining the use of whole exome sequencing to screen newborns for genetic childhood disease risk. In addition to studying risks and benefits, BabySeq follows the pediatricians’ incorporation of genetic information into the baby’s medical care. The first study of its kind, BabySeq aims to collect the data needed to examine what the risks and benefits of newborn genome sequencing might be as we imagine implementing into into everyday care.
The MilSeq Project, funded by the Department of Defense through the Air Force Medical Support Agency, is a pilot study examining the process of incorporating whole exome sequencing (WES) into the United States Air Force (USAF) military health system. Active-duty service members of the USAF (Airmen) are enrolled into the study to undergo clinical WES. Reports are then returned directly to Airmen by military healthcare providers.
The Personal Genome Sequencing Outcomes (PeopleSeq) Consortium, funded by the NIH, is one of the first large-scale longitudinal studies to examine the experiences, attitudes and outcomes of apparently healthy adults who have elected to obtain exome or genome sequencing. Data collected will provide valuable information on the potential benefits and costs of performing sequencing in healthy individuals, and key insights into the feasibility of using sequencing to create a more personalized and preventative model of medicine.