Genome sequencing (GS) is increasingly conducted in large-scale human research studies, creating questions for investigators about whether and how to return genetic findings. The American College of Medical Genetics and Genomics (ACMG) recommends that physicians report secondary findings in at least 59 actionable genes (the ACMG59) whenever clinical GS is ordered. In an effort to … Continued
The BabySeq Project, funded by the NIH, is examining the use of whole exome sequencing to screen newborns for genetic childhood disease risk. BabySeq follows the pediatricians’ incorporation of genetic information into the baby’s medical care. BabySeq aims to collect the data needed to examine what the risks and benefits of newborn genome sequencing might be as we imagine implementing into everyday care.
The MilSeq Project, funded by the Department of Defense through the Air Force Medical Support Agency, is a pilot study examining the process of incorporating whole exome sequencing (WES) into the United States Air Force (USAF) military health system. Active-duty service members of the USAF (Airmen) are enrolled into the study to undergo clinical WES.