Polygenic risk scores
What a Polygenic Risk Score Can and Can’t Tell You
“Scientists have made great strides in predicting the genetic risk of common diseases. Figuring out what to do with that information may be just as hard.” In this piece from Harvard Medicine, Robert Green, MD, MPH discusses the clinical utility of polygenic risk scores, drawing on his experience returning these results to patients in the … Continued
G2P June Newsletter 2024
Our June newsletter highlights the upcoming International Conference on Newborn Sequencing and several stories from recent trainees! Other updates include two new publications from G2P team members, Sophia Adelson and Anna Lewis. Finally, we give a shout out to the members of our team who will be Running4Research at the upcoming 10K in Boston.
Managing differential performance of polygenic risk scores across groups: real-world experience of the eMERGE Network
The GenoVA study: Equitable implementation of a pragmatic randomized trial of polygenic-risk scoring in primary care
Perceived benefits and barriers to implementing precision preventive care: Results of a national physician survey
Primary care physician use of patient race and polygenic risk scores in medical decision-making
Navigating the uncertainty of precision cancer screening: The role of shared decision-making
Returning integrated genomic risk and clinical recommendations: The eMERGE study
Prioritizing the detection of rare pathogenic variants in population screening
Patient and provider perspectives on polygenic risk scores: Implications for clinical reporting and utilization
Performance of EHR classifiers for patient eligibility in a clinical trial of precision medicine
Atria Institute Vanguard Symposia: The Path to Preventive Genomics
“In this episode, leading medical geneticist Dr. Robert Green guides listeners through the transformative potential of genomics for personalized medicine, exploring the shift from diagnosing rare conditions to predicting common diseases. He discusses the rise of preventive genomics clinics and how detailed genetic insights can guide medical decisions, including medication selection and dosage. Dr. Green … Continued




























