Genomic risk model to implement precision prostate cancer screening in clinical care: theProGRESS study

Vassy JL Dornisch AM Karunamuni R Gatzen M Kachulis CJ Lennon NJ Brunette CA Danowski ME Hauger RL Garraway IP Kibel AS Lee KM Lynch JA Maxwell KN Ratner D Rose BS Teerlink CC Xu GJ Hofherr SE Lafferty KA Larkin K Malolepsza E Patterson CJ Toledo DM Donovan JL Hamdy FC Martin RM Neal DE Turner EL Andreassen OA Dale AM Mills IG Abraham A Batra J Clements J Cussenot O Cybulski C Eeles RA Fowke JH Grindedal EM Grönberg H Hamilton RJ Lim J Lu YJ MacInnis RJ Maier C Mucci LA Multigner L Neuhausen SL Nielsen SF Parent MÉ Park JY Petrovics G Plym A Razack A Rosenstein BS Schleutker J Sørensen KD Townsend PA Travis RC Vega A West CML Wiklund F Zheng W Seibert TM Profile SteeringCommittee IMPACT Study Steering Committee and Collaborators PRACTICAL Consortium VA Million VeteranProgram Seiber TM
Nature Cancer January 2026  

What a Polygenic Risk Score Can and Can’t Tell You

Harvard Medicine |
August 2024
Press

“Scientists have made great strides in predicting the genetic risk of common diseases. Figuring out what to do with that information may be just as hard.” In this piece from Harvard Medicine, Robert Green, MD, MPH discusses the clinical utility of polygenic risk scores, drawing on his experience returning these results to patients in the … Continued

G2P June Newsletter 2024

G2P News |
June 2024
G2P News

Our June newsletter highlights the upcoming International Conference on Newborn Sequencing and several stories from recent trainees! Other updates include two new publications from G2P team members, Sophia Adelson and Anna Lewis. Finally, we  give a shout out to the members of our team who will be Running4Research at the upcoming 10K in Boston.

Returning integrated genomic risk and clinical recommendations: The eMERGE study

Linder JE, Allworth A, Bland HT, Caraballo PJ, Chisholm RL, Clayton EW, Crosslin DR, Dikilitas O, DiVietro A, Esplin ED, Forman S, Freimuth RR, Gordon AS, Green R, Harden MV, Holm IA, Jarvik GP, Karlson EW, Labrecque S, Lennon NJ, Limdi NA, Mittendorf KF, Murphy SN, Orlando L, Prows CA, Rasmussen LV, Rasmussen-Torvik L, Rowley R, Sawicki KT, Schmidlen T, Terek S, Veenstra D, Velez Edwards DR, Absher D, Abul-Husn NS, Alsip J, Bangash H, Beasley M, Below JE, Berner ES, Booth J, Chung WK, Cimino JJ, Connolly J, Davis P, Devine B, Fullerton SM, Guiducci C, Habrat ML, Hain H, Hakonarson H, Harr M, Haverfield E, Hernandez V, Hoell C, Horike-Pyne M, Hripcsak G, Irvin MR, Kachulis C, Karavite D, Kenny EE, Khan A, Kiryluk K, Korf B, Kottyan L, Kullo IJ, Larkin K, Liu C, Malolepsza E, Manolio TA, May T, McNally EM, Mentch F, Miller A, Mooney SD, Murali P, Mutai B, Muthu N, Namjou B, Perez EF, Puckelwartz MJ, Rakhra-Burris T, Roden DM, Rosenthal EA, Saadatagah S, Sabatello M, Schaid DJ, Schultz B, Seabolt L, Shaibi GQ, Sharp RR, Shirts B, Smith ME, Smoller JW, Sterling R, Suckiel SA, Thayer J, Tiwari HK, Trinidad SB, Walunas T, Wei WQ, Wells QS, Weng C, Wiesner GL, Wiley K, eMERGE Consortium, Peterson JF
Genetics in Medicine January 2023  

Atria Institute Vanguard Symposia: The Path to Preventive Genomics

Atria |
May 2022
Video

“In this episode, leading medical geneticist Dr. Robert Green guides listeners through the transformative potential of genomics for personalized medicine, exploring the shift from diagnosing rare conditions to predicting common diseases. He discusses the rise of preventive genomics clinics and how detailed genetic insights can guide medical decisions, including medication selection and dosage. Dr. Green … Continued

Development of clinical polygenic risk score assay and report

Hao L, Kraft P, Berriz G, Hynes ED, Koch C, Kumar PKV, Parpattedar SS, Steeves M, Yu W, Antwi AA, Brunette CA, Danowski M, Gala MK, Green RC, Jones NE, Lewis ACF, Lubitz SA, Natarajan P, Vassy JL, Lebo MS
Nature Medicine | PMID: 35437332 April 2022