The Second Revolution of Newborn Screening

Medium |
July 2024
G2P Blog

Visiting researcher, José Manuel González de Aledo Castillo, speaks on what newborn sequencing programs can learn from conventional newborn screening in his recent blog entitled “The Second Revolution of Newborn Screening.” He advocates for a future in which newborn sequencing and traditional newborn screening can work together in a complementary manner to ultimately reduce costs … Continued

G2P June Newsletter 2024

G2P News |
June 2024
G2P News

Our June newsletter highlights the upcoming International Conference on Newborn Sequencing and several stories from recent trainees! Other updates include two new publications from G2P team members, Sophia Adelson and Anna Lewis. Finally, we  give a shout out to the members of our team who will be Running4Research at the upcoming 10K in Boston.

Genome Sequencing for Kids – Robert Green

Deep Future |
June 2024
Podcast

Robert Green joins Pablos Holman on the Deep Future podcast to discuss the promise of genome sequencing in children. He draws upon his work from the BabySeq Project and from his new start-up company, Nurture Genomics, where he uses genomic screening in infants to detect and mitigate actionable genetic conditions.

The DNA Test Delusion

Bloomberg |
May 2024
Press

Will DNA tests like 23andMe actually help people live longer and healthier lives? This article dives into the promises and challenges of using DNA tests to improve health. Robert Green comments on his new company, Nurture Genomics, and explains that, “If you combine genetic risk with targeted care and surveillance for those individuals at higher … Continued

Interview: Nina Gold

European Medical Journal |
March 2024
Press

In this interview with the European Medical Journal, Dr. Nina Gold reflects on what inspired her career in pediatric genetics. She describes her work in clinical and research settings, particularly in the context of newborn genomic screening.

G2P March Newsletter 2024

G2P News |
March 2024
G2P News

Genomes2People’s first newsletter of 2024 highlights presentations at the ACMG Annual Clinical Genetics Meeting from several G2P collaborators including Ilham Abbasi, Dr. Nina Gold, and Dr. Kurt Christensen. The piece also highlights Dr. Robert Green’s recent interview with CBS News on Rare Disease Day that showcases findings and stories from the BabySeq Project. The newsletter … Continued

How Genomics Could Save Your Life

Medium |
February 2024
G2P Blog

In this blog post, Dr. Robert Green poses the question: “What’s holding us back from doing more with preventive genomics in medicine?” Drawing on his recent keynote talk at the Precision Medicine Network (PMNET) Forum in Riga, Latvia, Dr. Green explores near-term applications of precision medicine using genetic testing such as: newborn and childhood sequencing, … Continued

Your Baby’s Genome: The Radical Promise of Early DNA Testing

Cure. |
January 2024
Video

Robert Green is interviewed by Seema Kumar, Cure CEO about The Radical Promise of Early DNA Testing for human health and longevity. He shares results from the BabySeq Project and progress on building the new start-up company, Nurture Genomics.

G2P December Newsletter 2023

G2P News |
December 2023
G2P News

G2P’s final newsletter of 2023 celebrates the five year anniversary of The Franca Sozzani Fund for Preventive Genomics. Other highlights include the second annual meeting of the International Consortium on Newborn Sequencing (ICoNS) in London and the 2023 Advisory Board members of the year, Mike and Ann Marie Einziger. We also join Genomes2Veterans in celebrating … Continued

BabySeq, ICoNS and the power of newborn sequencing: Q&A with Dr Robert Green

Lab Insights |
December 2023
Video

“In this Q&A with Will Greene, Healthcare Engagement Lead at Roche Diagnostics Asia Pacific, Dr Green talks about his pioneering work in newborn sequencing, including via the BabySeq project and the International Consortium on Newborn Sequencing (ICoNS), as well as his broader efforts to make genomic information actionable and accessible for people everywhere.”

Broad Institute Rebrands Clinical Lab Services to Be ‘a Little Bit More Out There’

GenomeWeb |
November 2023
Press

“Robert Green, a professor at Harvard Medical School and co-PI of the BabySeq2 study, said the project picked the Broad lab as its sequencing provider, while the Mass General Brigham Laboratory for Molecular Medicine (LMM) is doing the genome interpretation. The project, which is currently recruiting, intends to enroll between 500 and 2,000 families over … Continued

Newborn Sequencing 2023 Part II: What Evidence Is Enough?

Mendelspod |
November 2023
Podcast

Julia Karow, Managing Editor at GenomeWeb; Robert Green, Director of Genomes2People and Co-Chair of the International Consortium on Newborn Sequencing (ICoNS); Wendy Chung, Chair of Pediatrics in Medicine at Boston Children’s Hospital and leader of the Guardian Study; and James Buchanan, Senior Lecturer in Health Economics at Queen Mary University in London, discuss takeaways and … Continued

Global leaders convene in London: Advancing newborn sequencing on an international scale

Medium |
October 2023
G2P Blog

Earlier this month, leading researchers and experts in genomics and newborn sequencing representing the U.S., the U.K., Europe, Australia, and the Middle East came together in London at the Royal Institution for the second annual International Conference on Newborn Sequencing co-hosted with Genomics England to present updates regarding their own research and share future plans.

Five Year Follow-Up to BabySeq Project

PMNET Forum |
October 2023
Video

The 2023 Precision Medicine Network (PMNET) Forum was held on October 12-13, 2023 in Riga, Latvia. PMNET’s mission is to improve patient care and outcomes by promoting development and adoption of Precision Medicine. Robert Green gave a talk about the five year follow-up of the BabySeq Project.

International newborn genome sequencing projects discuss differences, future goals

GenomeWeb |
October 2023
Press

Last week a dozen newborn sequencing research programs from the US, the UK, Europe, Australia, and the Middle East shared progress updates and future plans at the second annual International Conference on Newborn Sequencing (ICoNS) in London. Robert Green and Ingrid Holm, co-PIs of the BabySeq2 study, shared enrollment updates from the second iteration of … Continued

BabySeq Project Update at ICoNS’23

International Consortium on Newborn Sequencing |
October 2023
Video

At the 2023 International Conference on Newborn Sequencing (ICoNS), Drs. Robert Green and Ingrid Holm, Co-PIs of BabySeq2, share updates on the BabySeq Project.

ICoNS’23: Up/Downstream Ecosystem Panel

International Consortium on Newborn Sequencing |
October 2023
Video

At the 2023 International Conference on Newborn Sequencing (ICoNS), Dr. Robert Green moderates a panel on the up and downstream ecosystem of newborn sequencing. Panelists include Dr. Vanessa Almendro from Danaher Corp, Dr. Paul Kruszka from GeneDx, and Dr. Jennifer Ibrahim from Sanofi.

ICoNS’23 Introduction with Drs. Robert Green and David Bick

International Consortium on Newborn Sequencing |
October 2023
Video

Drs. Robert Green and David Bick, Co-Chairs of the International Consortium on Newborn Sequencing, share their introductory remarks at the start of ICoNS’23 in London, UK.

Bringing equity to genomic sequencing in newborns: BabySeq 2.0

Boston Children's Hospital |
October 2023
Press

Read about how the second iteration of The BabySeq Project, BabySeq 2.0, is striving to make genome sequencing accessible to a diverse population of newborns at Boston Children’s Hospital and other sites around the country. Ingrid Holm, MD, MPH who co-leads BabySeq 2.0 describes how seeking input from a Community Advisory Board from each participating … Continued

G2P September Newsletter 2023

September 2023
G2P News

This newsletter highlights the International Conference on Newborn Sequencing (ICoNS) that is just around the corner on October 5-6, 2023 in London, UK. It’s not too late to register! Other G2P updates include media coverage of BabySeq1 publications, a new publication from the Sanford Imagenetics team about pharmacogenomics in primary care, and a blog post … Continued

Newborn Screening and Genomics with Robert C. Green, MD, MPH

Ambry Genetics |
August 2023
Video

In this webinar Dr. Green explores the path towards a more personalized and preventive approach to medicine. He draws on insights gained from the MedSeq and BabySeq projects led by the Genomes2People Research Program (G2P).

Genomic newborn screening: current concerns and challenges

The Lancet |
July 2023
Press

A recent editorial by The Lancet dives into the debate on universal newborn sequencing. While using genome sequencing as a screening tool for newborns has the potential to offer a great deal of relevant health information, there are certainly ethical issues and other challenges that also need to be addressed. The BabySeq Project is cited … Continued

G2P July Newsletter 2023

July 2023
G2P News

In this newsletter we’re excited to announce that the Precision Population Health initiative (PPH) is working with the South Central Foundation (SCF) on a new clinical genomic screening program to improve the health of the Alaska Native population. We are also thrilled to share that registration for the Second Annual International Conference on Newborn Sequencing … Continued

Panel Discussion at NASEM Workshop: Next-Generation Screening – The Promise and Perils of DNA Sequencing of Newborns at Birth

The National Academies |
June 2023
Video

During the first session of the National Academies of Sciences, Engineering, and Medicine Workshop entitled Next-Generation Screening – The Promise and Perils of DNA Sequencing of Newborns at Birth, Robert Green participated alongside Ellen Wright Clayton, Crystal Grant, and Mike Hu in a panel discussion moderated by Karen Weck.

Next-generation screening – The promise and perils of DNA sequencing of newborns at birth

The National Academies |
June 2023
Video

During the second session of the National Academies of Sciences, Engineering, and Medicine Workshop entitled Next-Generation Screening – The Promise and Perils of DNA Sequencing of Newborns at Birth, Robert Green shared updates from the BabySeq project in his presentation: Empirical Data on the Path to Universal Newborn Sequencing. Recorded sessions of the entire NASEM workshop … Continued

DNA sequencing in newborns reveals years of actionable findings for infants and families

Brigham and Women's Hospital |
June 2023
Press Release

“By screening apparently healthy newborns, entire families were alerted for the first time that dangerous but treatable genetic variants were present,” said corresponding author Robert C. Green, MD, MPH, a physician-scientist at Brigham and Women’s Hospital and professor of genetics at Harvard Medical School, who leads the BabySeq Project. “We were stunned to see that … Continued

The Path to Universal Newborn Sequencing

Newborn Screening Translational Research Network |
May 2023
Video

On May 18-19, 2023 from 12-4pm (EST), the Newborn Screening Translational Research Network (NBSTRN) hosted a two-day virtual meeting that showcased the important role of advocacy and research in NBS. Robert Green, MD, MPH led a talk on the path to universal newborn sequencing.

Genetics experts support adding hundreds of treatable rare diseases to newborn screening

National Center for Advancing Translational Sciences |
May 2023
Press

“In a newly released study, nearly nine of 10 experts on rare diseases agreed that sequencing healthy newborns’ DNA to reveal treatable genetic disorders should be available for all infants. At least half of experts also endorsed testing for more than 400 genes as part of such newborn genomic screens. These NCATS-supported study results might … Continued

Should all U.S. newborns undergo genomic testing?

U.S. News & World Report |
May 2023
Press

“While newborns are only screened for about 60 treatable conditions, there are hundreds of genetic disorders that have targeted treatments. Now, a national survey of experts in rare diseases found the vast majority support DNA sequencing in healthy newborns…’It has been a longstanding dream to someday offer DNA sequencing to all newborns in order to … Continued

Rare disease experts support newborn genome sequencing

Inside Precision Medicine |
May 2023
Press

“Research led by Mass General Hospital for Children suggests that almost 90% of rare disease experts are in favor of newborn genome sequencing for monogenic treatable disorders…’Early identification of infants who are at risk for genetic disorders can be lifesaving and screening has the potential to improve healthcare disparities for affected children,’ said lead author … Continued

Rare-disease doctors support expanded newborn genomic screening, survey finds

STAT |
May 2023
Press

“When 238 rare-disease doctors across the U.S. were surveyed by a research team at Mass General Brigham in Boston, 88% of them agreed that DNA sequencing to screen for certain treatable childhood disorders should be made available to all newborns. The study was published Monday in JAMA Network Open.”

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