In this study led by UCSF researchers, exome sequencing was found to produce more false positives and false negatives for inherited metabolic disorders than the standard blood testing conducted in newborns. G2P’s Dr. Robert Green, co-leader of the BabySeq Project, speaks to the possibility “that the most comprehensive screening for newborns will be some combination … Continued
In the first of a two-part series, AMA Chief Experience Officer Todd Unger discusses genetics at play in COVID-19 with experts Wendy Chung, MD, PhD, Robert Green, MD, MPH, and AMA’s Chief Health and Science Officer Mira Irons, MD.
Boston researchers using COVID-19 patients’ DNA to unlock secrets about impact of virus
To help scientists around the globe study Covid-19, researchers in Boston have shared genetic and other clinical data from thousands of patients with an international consortium. That data includes information from dozens of people with Covid-19, who had donated blood samples and opened up their medical records before the pandemic.
Dr. Robert Green is the director of the Preventive Genomics Clinic at Brigham and Women’s Hospital in Boston. He believes that DNA testing combined with proper counseling and medical follow-up would be a critical element of a healthcare system that can prevent illness.
Our genes might make some of us more susceptible to COVID-19—but which genes? Geneticists are sharing their vast DNA databases to find out.
“..There are researchers – every single scientist is thinking ‘how can I contribute?’”
“While healthy young people as a group are less likely to have severe symptoms with COVID, they have to understand that some of them will become very ill and will even die from this infection,” Dr. Robert Green said. “No one should assume youth makes them invulnerable.”
An exclusive Clinical OMICs conversation with the director of Genomes2People, Robert Green, M.D., MPH
Through national research efforts like the All of Us Research Program, Brigham investigators and their collaborators are making genomic research more meaningful, equitable and impactful for all patients at the Brigham and around the world.
Whole genome tests can help identify the cause of a baby’s mysterious illness. But ethicists say it’s still too soon to use them for all infants.
“Our research is finding that genetics is about to take its rightful place in medical care for the world.” said Dr. Robert Green, a professor of genetics at Harvard Medical School.
Companies claim they can now easily calculate your biological age. Should you take them up on it?
A new epigenetic test that tracks molecular aging claims to show you how to stay biologically young. However, Robert Green says “epigenetic marks in apparently healthy people can tell them meaningful things about their health status is an overreach.”
“It’s really exciting that to see companies move to preserve health, rather than just treating patients when they’re ill,” said Dr. Robert Green, a medical geneticist at Harvard Medical School and a co-founder of a genetics company called Genome Medical.
We now have the ability to screen for thousands of genetic diseases in newborns. That may not always be the healthy thing to do.
Genetic counselors are becoming a bigger part of the healthcare continuum as population health management seeks to more quickly screen for, assess and prevent illness. Read on as genetic counselors in the field, including our own, Carrie Blout, address some of the barriers in genetic counseling.
BGI is racing toward a world where your DNA informs your medical decisions—and maybe some of your personal ones. Bloomberg asks Dr. Robert Green on his thoughts regarding the medical advances in genomics in China and how they compare to those in the US.
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Genetic scans provide lots of information, but only a fraction is returned to patients. Dr. Robert Green states “It’s their body and their DNA. We have a responsibility to scientific truth and clear communication.”
“Preventive genomics is not yet recommended as standard of care,” Robert Green, director of the Preventive Genomics Clinic, said in a statement. “But for over two decades, our NIH-funded, randomized trials in translational genomics have generated consistent evidence that there are more potential medical benefits and fewer risks than previously considered. It is time for … Continued
Brigham and Women’s Hospital has launched the Preventive Genomics Clinic, a facility designed to provide comprehensive DNA sequencing, interpretation and reporting of disease-associated genes.
Dr. Jason Vassey was announced as one of six recipients for the Genomic Innovator supporting early career investigators researching genome biology, genomic medicine, technology development and societal implications of genomic advances.
Researchers led by Robert Green at Brigham and Women’s Hospital looked at whether consumers getting direct-to-consumer genetic testing were using PGx tests to change treatment decisions. Although this study relied on self-reported data from participants, it suggests that less than 1 percent could have made unsupervised medication changes based on their genetic test results.
Brigham and Women’s Hospital on Friday unveiled a new Preventive Genomics Clinic that will offer a menu of options for a genetic workup, with price tags ranging from $250 to $2,950, depending on how many genes are analyzed; it’s the first program of its kind that will offer the sequencing to children in addition to adults.
The preventive genomics clinic is offering what’s arguably the opposite of modestly priced, do-it-yourself tests: It’s a full-service genomics clinic for patients who want the elite care of an academic medical center and will pay for it out of pocket.
“I would have never known that I was at risk if i hadn’t donated to the Biobank,” said Kristine Trudeau who knowingly enrolled in the Partners HealthCare Biobank because she wanted to help advance medicine and potentially save lives. She did not expect that it would save her own.
The first major randomized clinical trial on the effect of disclosing genetic information found that people who decided to learn about their genetic risk of developing Alzheimer’s disease did not experience large, negative psychological impacts.
More and more people want to explore their own medical data, and a DTC genetic test is one way to begin to understand some aspects of your future health.
At a new clinic in Boston, genetic counselor Carrie Blout helps healthy patients get their DNA tested for predispositions to more than 2500 diseases. Bloomberg’s Aki Ito goes through the testing herself, trialing a controversial technology at the forefront of modern medicine.
Babies are tested for a number of conditions soon after birth, but varied approaches to screening worldwide highlight how fragmented the medical profession remains over this vital process.
MIT scientists used a novel tool to try to edit out a genetic risk for Alzheimer’s disease, they report in the journal Science. Dr. Robert Green gives his opinion on the new technology.
Dr. Robert Green on learning of your genetic risk to developing Alzheimer’s quotes: “Not everything has a pill or medical-prevention plan, but many information-seeking persons can find all sorts of benefits in better understanding their risk of future disease.”
Its screen for selected variants of some disease-linked genes gives customers an incomplete picture of their risk—do they know?
A decade ago, it seemed inevitable that every newborn would get a complete gene scan. But there are technical challenges and practical concerns.Dr. Robert Green, from Brigham and Women’s Hospital in Boston, voiced one view about doing that: “If sequencing reveals health risks at any point in life, and if that’s good, then it’s better … Continued
Kristine Trudeau agreed to donate a sample of blood to the Partners HealthCare Biobank, a resource for researchers across the Partners hospital network — including the Brigham and Massachusetts General. By analyzing large numbers of blood samples, scientists can learn how genes contribute to disease. Trudeau shares her experiences as being one the many participants … Continued
Robert Green, MD, MPH, of the Division of Genetics, was included in BIS Research and Insight Monk’s Top 25 Voices in Precision Medicine for his work on medical genetics and genomics.