Return of individual research results from genomic research: A systematic review of stakeholder perspectives
PLOS One
In Press
Return of incidental/unanticipated omics
Diverse Boston neighborhoods recruited for sweeping study of genetics and health outcomes
GBH News |
September 2021
Press, Radio
“Medical researchers in Boston are helping sign up one million volunteers for a first-of-its-kind study [The All of Us Research Program] examining the link between genes and our health. Researchers are actively recruiting volunteers of different races and ethnicities to ensure that the study reflects the diversity of the United States.”
Using the Alzheimer’s Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer’s disease
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
September 2021
Sequencing every newborn’s genome to detect diseases faces ethical and practical obstacles, but the United Kingdom is pushing ahead with a major test
Science |
September 2021
Press
Genomic testing for Baby Cora, a participant of The BabySeq Project, revealed a disorder that might otherwise have gone undetected through traditional newborn screening. “Cora’s case illustrates the promise of sequencing the entire genomes of newborns: uncovering a bounty of genetic information that could identify infants needing treatment and improve health later in life…Genomics England … Continued
Returning actionable genomic results in a research biobank: Analytic validity, clinical implementation and resource utilization
American Journal of Human Genetics
In Press
Re-evaluating the “right not to know” in genomics research
Genetics in Medicine
In Press
Controversy flares over informing research subjects about ‘incidental’ genetic findings
American Association for the Advancement of Science |
August 2021
Press
“Should people who volunteer for genomic studies be told about unrelated disease mutations that turn up in their sequence data?”
G2P Newsletter July 2021
July 2021
G2P News
Our G2P research team continues to be extraordinarily productive, publishing 21 scientific papers so far this year. This summer newsletter highlights a few of these papers, as well as G2P media features, blog posts, and policy recommendations.
An international policy on returning genomic research results
Genome Medicine
July 2021
Primary care providers’ responses to unsolicited Lynch syndrome secondary findings of varying clinical significance
Genetics in Medicine
June 2021
Precision Population Health initiative targets precision medicine delivery in primary care
Healthcare Innovation |
March 2021
Press
Joint project between Ariadne Labs and Genomes2People to create implementation pathways, tools and guides that work across various clinical contexts.
Combining science and service as a VA genetic counselor
VAntage Point |
March 2021
Press
“In 2019, [G2V’s] Morgan Danowski graduated and joined Boston VA. There, she supports VA’s Million Veteran Program (MVP), now the world’s largest genomics research program. The program takes DNA from participating Veterans and information on their health, lifestyle and military experiences and exposures to better understand disease in Veteran populations. With over 830,000 Veterans enrolled, … Continued
G2P Newsletter October 2020
October 2020
G2P News
Over the past few months, G2P faculty have attended numerous virtual conferences, been featured in the news and media, and contributed to studies involving the role of genetics in COVID-19. Many of our presentations are transitioning to a virtual format and shared on YouTube for all to view; make sure to check out our presentations … Continued
Understanding the return of genomic sequencing results process: Content review of participant summary letters in the eMERGE research network
Journal of Personalized Medicine
May 2020
Returning results in the genomic era: Initial experiences of the eMERGE network
Journal of Personalized Medicine
April 2020
The case for implementing sustainable routine, population-level genomic reanalysis
Genetics in Medicine
December 2019
Harmonizing clinical sequencing and interpretation for the eMERGE III network
American Journal of Human Genetics
August 2019
Partners Biobank surpasses 100,000 participants
Brigham Bulletin |
August 2019
Press
“I would have never known that I was at risk if i hadn’t donated to the Biobank,” said Kristine Trudeau who knowingly enrolled in the Partners HealthCare Biobank because she wanted to help advance medicine and potentially save lives. She did not expect that it would save her own.
Blood samples reveal valuable data — and life-changing surprises for donors
The Boston Globe |
July 2019
Press
Kristine Trudeau agreed to donate a sample of blood to the Partners HealthCare Biobank, a resource for researchers across the Partners hospital network — including the Brigham and Massachusetts General. By analyzing large numbers of blood samples, scientists can learn how genes contribute to disease. Trudeau shares her experiences as being one the many participants … Continued
How frequently should genomic results be updated?
Medium |
June 2019
G2P Blog
Continuous new discoveries about the genome make updates important.
Analyzing and reanalyzing the genome: Findings from the MedSeq project
American Journal of Human Genetics
June 2019
Sanford Health taps Harvard, Brigham and Women’s for genetic screening study
Genome Web |
June 2019
Press
Under the four-year collaboration, experts in genomic medicine from Harvard and Brigham and Women’s will help guide Sanford researchers in using and interpreting data collected through the Sanford Chip, a $49 pharmacogenomic test to identify genetic risk factors for medication use and more accurately prescribe medications.
G2P Newsletter March 2019
March 2019
G2P News
Spring saw accomplishments by team members through numerous projects. G2P officially kicked-off the PeopleSeq consortium in Boston this January! Our very own, Carrie Blout, MS, CGC, was one of 86 Partner’s individuals awarded the Partners In Excellence Award.
Dr. Robert Green on the impact of individual genomic data
Harry Glorikian |
December 2018
Podcast
Harry Glorikian guest this week, Dr. Robert Green, is a professor of medicine and genetics at Harvard Medical School and director of the Genomes To People research program at Brigham & Women’s Hospital and the Broad Institute of Harvard and MIT. They dig into the individual genome, how genomic data is being used, and the impact … Continued
G2P Newsletter December 2018
December 2018
G2P News
This Fall, G2P has had exciting updates with a new PeopleSeq grant. Our team has traveled from San Diego, Atlanta, and Fort Detrick to Basel, Zurich, and Barcelona, to several conferences, presenting new data from our translational genomics research projects.
Reconciling opportunistic and population screening in clinical genomics
Mayo Clinic Proceedings
January 2019
BabySeq, MedSeq projects reveal how many people carry genetic risk variants for rare diseases
Brigham Women's Hospital |
October 2018
Press Release
More information on newborn and adult sequencing studies unveiled at the 2018 American Society for Human Genetics Meeting in San Diego, CA. Two projects in which healthy individuals have had their genomes sequenced have revealed that searching for unanticipated genetic results in newborns and adults can unearth far more variants associated with diseases than previously thought, … Continued
Millions of Americans could be identified using consumer genetic databases—even if they’ve never taken a DNA test
Time |
October 2018
Press
“All of the crimes that are currently unsolved, which have DNA evidence, there’s now a pathway to trying to locate these perpetrators,” says Dr. Robert Green, a medical geneticist at Brigham and Women’s Hospital and a professor at Harvard Medical School.
Plenary presentation at the Advances in Genome Biology and Technology Precision Health Meeting
AGBT Precision Health Conference |
September 2018
Video
Dr. Robert C. Green speaks at the 2018 Advances in Genome Biology and Technology (AGBT) Precision Health Conference in San Diego, California about our efforts to gather empirical data on genome sequencing healthy individuals. Watch to learn more about G2P’s MilSeq, BabySeq, MedSeq, PeopleSeq, PGen and REVEAL projects. Click here for more on the conference.
Approaches to carrier testing and results disclosure in translational genomics research: The clinical sequencing exploratory research consortium experience
Molecular Genetics & Genomic Medicine
August 2018
My ancestry test revealed a genetic bombshell
New York Post |
August 2018
Press
Ancestry tests have “blown up family secrets all over the country”, but is it really helping people for the better to know this information? Read about Dr. Robert Green’s opinions on genomic testing revealing unsuspected familial matters.
Challenging the current recommendations for carrier testing in children
Pediatrics
January 2019
Privacy and consumer genetic testing don’t always mix
ScienceNews |
June 2018
Press
For a few hundred dollars and a spit sample, you too could take a journey of genetic self-discovery. You may learn some things, but what are you giving away? Before you spit, it helps to know what you’re getting into.
Genome sequencing for healthy people: Will it be harmful?
Medium |
March 2018
G2P Blog
The second piece of a 2-part blog series authored by Dr. Robert C. Green. An early study found no problems related to unnecessary or harmful medical follow-ups after healthy people received their genome sequencing results. To read the first piece, visit: https://medium.com/@genomes2people/genome-sequencing-for-healthy-people-will-it-be-helpful-b984b94e3d3f
Genome sequencing for healthy people: Will it be helpful?
Medium |
February 2018
G2P Blog
The first piece of a 2-part blog series authored by Dr. Robert C. Green. Early results suggest that yes, whole genome sequencing may very well be substantially helpful to a significant number of healthy patients. To read the second piece, visit: https://medium.com/@genomes2people/genome-sequencing-for-healthy-people-will-it-be-harmful-d915cc08e634
Preferences for the return of individual results from research on pediatric biobank sample
Journal of Empirical Research on Human Research Ethics
April 2017
