Elective genomic sequencing for adults in research, clinical and commercial contexts

Linderman MD, Adelson SM, Berro TM, Anderson JL, Crawford SD, Cunningham TJ, Esplin ED, Ewing-Crawford AT, Nielsen DE, Pereira S, Schmidlen T, Andrighetti H, Bleyl SB, Church GM, Haverfield EV, Hegde M, Konstantinos LN, Kruszka P, Leonard D, May T, McGinniss M, Pandya V, Schadt EE, Tzovaras BG, Zettler B, McGuire AL, Green RC and the PeopleSeq Study Team
BMC Medical Genomics In Press

Newborn Genomic Screening Takes Center Stage at ACMG as Stakeholders Discuss Progress, Concerns

GenomeWeb |
March 2026
Press

As newborn genomic screening initiatives continue to unfold around the world, the ethical and responsible implementation of the approach into public health sparked vibrant discussions at the American College of Medical Genetics and Genomics (ACMG) annual meeting last week. In addition to updates from notable newborn genomic screening studies — such as the UK’s Generation … Continued

Genome Sequencing for Kids – Robert Green

Deep Future |
June 2024
Podcast

Robert Green joins Pablos Holman on the Deep Future podcast to discuss the promise of genome sequencing in children. He draws upon his work from the BabySeq Project and from his new start-up company, Nurture Genomics, where he uses genomic screening in infants to detect and mitigate actionable genetic conditions.

G2P March Newsletter 2024

G2P News |
March 2024
G2P News

Genomes2People’s first newsletter of 2024 highlights presentations at the ACMG Annual Clinical Genetics Meeting from several G2P collaborators including Ilham Abbasi, Dr. Nina Gold, and Dr. Kurt Christensen. The piece also highlights Dr. Robert Green’s recent interview with CBS News on Rare Disease Day that showcases findings and stories from the BabySeq Project. The newsletter … Continued

Development and utility of a clinical research informatics application for participant recruitment and workflow management for a return of results pilot trial in familial hypercholesterolemia in the Million Veteran Program

Brunette CA, Yi T, Danowski ME, Cardellino M, Harrison A, Assimes TL, Knowles JW, Christensen KD, Sturm AC, Sun YV, Hui Q, Pyarajan S, Shi Y, Whitbourne SB, Gaziano JM, Muralidhar S, Vassy JL
Journal of the American Medical Informatics Association | PMID: 38464744 March 2024  

How Genomics Could Save Your Life

Medium |
February 2024
G2P Blog

In this blog post, Dr. Robert Green poses the question: “What’s holding us back from doing more with preventive genomics in medicine?” Drawing on his recent keynote talk at the Precision Medicine Network (PMNET) Forum in Riga, Latvia, Dr. Green explores near-term applications of precision medicine using genetic testing such as: newborn and childhood sequencing, … Continued

BabySeq, ICoNS and the power of newborn sequencing: Q&A with Dr Robert Green

Lab Insights |
December 2023
Video

“In this Q&A with Will Greene, Healthcare Engagement Lead at Roche Diagnostics Asia Pacific, Dr Green talks about his pioneering work in newborn sequencing, including via the BabySeq project and the International Consortium on Newborn Sequencing (ICoNS), as well as his broader efforts to make genomic information actionable and accessible for people everywhere.”

Five Year Follow-Up to BabySeq Project

PMNET Forum |
October 2023
Video

The 2023 Precision Medicine Network (PMNET) Forum was held on October 12-13, 2023 in Riga, Latvia. PMNET’s mission is to improve patient care and outcomes by promoting development and adoption of Precision Medicine. Robert Green gave a talk about the five year follow-up of the BabySeq Project.

The Path to Universal Genomic Medicine

PMNET Forum |
October 2023
Video

The 2023 Precision Medicine Network (PMNET) Forum was held on October 12-13, 2023 in Riga, Latvia. PMNET’s mission is to improve patient care and outcomes by promoting development and adoption of Precision Medicine. Robert Green shared a keynote talk during the introduction of the Forum entitled The Path to Universal Genomic Medicine.

Bringing equity to genomic sequencing in newborns: BabySeq 2.0

Boston Children's Hospital |
October 2023
Press

Read about how the second iteration of The BabySeq Project, BabySeq 2.0, is striving to make genome sequencing accessible to a diverse population of newborns at Boston Children’s Hospital and other sites around the country. Ingrid Holm, MD, MPH who co-leads BabySeq 2.0 describes how seeking input from a Community Advisory Board from each participating … Continued

Inside HGG Advances: A Chat with Nina Gold

American Society of Human Genetics |
September 2023
Press

Each month, the editors of Human Genetics and Genomics Advances interview an early-career researcher who has published work in the journal. This month they featured G2P collaborator Dr. Nina Gold to discuss her paper Phenotypes of undiagnosed adults with actionable OTC and GLA variants.

Newborn Screening and Genomics with Robert C. Green, MD, MPH

Ambry Genetics |
August 2023
Video

In this webinar Dr. Green explores the path towards a more personalized and preventive approach to medicine. He draws on insights gained from the MedSeq and BabySeq projects led by the Genomes2People Research Program (G2P).

G2P July Newsletter 2023

July 2023
G2P News

In this newsletter we’re excited to announce that the Precision Population Health initiative (PPH) is working with the South Central Foundation (SCF) on a new clinical genomic screening program to improve the health of the Alaska Native population. We are also thrilled to share that registration for the Second Annual International Conference on Newborn Sequencing … Continued

DNA sequencing in newborns reveals years of actionable findings for infants and families

Brigham and Women's Hospital |
June 2023
Press Release

“By screening apparently healthy newborns, entire families were alerted for the first time that dangerous but treatable genetic variants were present,” said corresponding author Robert C. Green, MD, MPH, a physician-scientist at Brigham and Women’s Hospital and professor of genetics at Harvard Medical School, who leads the BabySeq Project. “We were stunned to see that … Continued

The missing links: How to ensure omics data fulfills its promise

BioCentury |
May 2023
Press

“Omics data could herald a revolution in healthcare. The analysis of rich, interconnected and longitudinal multi-omics datasets promises a better understanding of the underlying biology of human health and disease, which in turn could lead to more effective prevention, earlier and more accurate diagnoses, new treatments and better choice of treatments. Despite that promise, only … Continued

Returning integrated genomic risk and clinical recommendations: The eMERGE study

Linder JE, Allworth A, Bland HT, Caraballo PJ, Chisholm RL, Clayton EW, Crosslin DR, Dikilitas O, DiVietro A, Esplin ED, Forman S, Freimuth RR, Gordon AS, Green R, Harden MV, Holm IA, Jarvik GP, Karlson EW, Labrecque S, Lennon NJ, Limdi NA, Mittendorf KF, Murphy SN, Orlando L, Prows CA, Rasmussen LV, Rasmussen-Torvik L, Rowley R, Sawicki KT, Schmidlen T, Terek S, Veenstra D, Velez Edwards DR, Absher D, Abul-Husn NS, Alsip J, Bangash H, Beasley M, Below JE, Berner ES, Booth J, Chung WK, Cimino JJ, Connolly J, Davis P, Devine B, Fullerton SM, Guiducci C, Habrat ML, Hain H, Hakonarson H, Harr M, Haverfield E, Hernandez V, Hoell C, Horike-Pyne M, Hripcsak G, Irvin MR, Kachulis C, Karavite D, Kenny EE, Khan A, Kiryluk K, Korf B, Kottyan L, Kullo IJ, Larkin K, Liu C, Malolepsza E, Manolio TA, May T, McNally EM, Mentch F, Miller A, Mooney SD, Murali P, Mutai B, Muthu N, Namjou B, Perez EF, Puckelwartz MJ, Rakhra-Burris T, Roden DM, Rosenthal EA, Saadatagah S, Sabatello M, Schaid DJ, Schultz B, Seabolt L, Shaibi GQ, Sharp RR, Shirts B, Smith ME, Smoller JW, Sterling R, Suckiel SA, Thayer J, Tiwari HK, Trinidad SB, Walunas T, Wei WQ, Wells QS, Weng C, Wiesner GL, Wiley K, eMERGE Consortium, Peterson JF
Genetics in Medicine January 2023  

Their DNA hides a warning, but they don’t want to know what it says

The New York Times |
January 2022
Press

The MGB Biobank returned actionable genetics results to 256 participants, 76.3 percent of whom were unaware that they carried a variant that put them at increased risk. The New York Times reports on this return of results process, outlining that some participants wanted to learn this information and others did not.