G2P March Newsletter 2024

G2P News |
March 2024
G2P News

Genomes2People’s first newsletter of 2024 highlights presentations at the ACMG Annual Clinical Genetics Meeting from several G2P collaborators including Ilham Abbasi, Dr. Nina Gold, and Dr. Kurt Christensen. The piece also highlights Dr. Robert Green’s recent interview with CBS News on Rare Disease Day that showcases findings and stories from the BabySeq Project. The newsletter … Continued

How Genomics Could Save Your Life

Medium |
February 2024
G2P Blog

In this blog post, Dr. Robert Green poses the question: “What’s holding us back from doing more with preventive genomics in medicine?” Drawing on his recent keynote talk at the Precision Medicine Network (PMNET) Forum in Riga, Latvia, Dr. Green explores near-term applications of precision medicine using genetic testing such as: newborn and childhood sequencing, … Continued

BabySeq, ICoNS and the power of newborn sequencing: Q&A with Dr Robert Green

Lab Insights |
December 2023

“In this Q&A with Will Greene, Healthcare Engagement Lead at Roche Diagnostics Asia Pacific, Dr Green talks about his pioneering work in newborn sequencing, including via the BabySeq project and the International Consortium on Newborn Sequencing (ICoNS), as well as his broader efforts to make genomic information actionable and accessible for people everywhere.”

Five Year Follow-Up to BabySeq Project

PMNET Forum |
October 2023

The 2023 Precision Medicine Network (PMNET) Forum was held on October 12-13, 2023 in Riga, Latvia. PMNET’s mission is to improve patient care and outcomes by promoting development and adoption of Precision Medicine. Robert Green gave a talk about the five year follow-up of the BabySeq Project.

The Path to Universal Genomic Medicine

PMNET Forum |
October 2023

The 2023 Precision Medicine Network (PMNET) Forum was held on October 12-13, 2023 in Riga, Latvia. PMNET’s mission is to improve patient care and outcomes by promoting development and adoption of Precision Medicine. Robert Green shared a keynote talk during the introduction of the Forum entitled The Path to Universal Genomic Medicine.

Bringing equity to genomic sequencing in newborns: BabySeq 2.0

Boston Children's Hospital |
October 2023

Read about how the second iteration of The BabySeq Project, BabySeq 2.0, is striving to make genome sequencing accessible to a diverse population of newborns at Boston Children’s Hospital and other sites around the country. Ingrid Holm, MD, MPH who co-leads BabySeq 2.0 describes how seeking input from a Community Advisory Board from each participating … Continued

Inside HGG Advances: A Chat with Nina Gold

American Society of Human Genetics |
September 2023

Each month, the editors of Human Genetics and Genomics Advances interview an early-career researcher who has published work in the journal. This month they featured G2P collaborator Dr. Nina Gold to discuss her paper Phenotypes of undiagnosed adults with actionable OTC and GLA variants.

Newborn Screening and Genomics with Robert C. Green, MD, MPH

Ambry Genetics |
August 2023

In this webinar Dr. Green explores the path towards a more personalized and preventive approach to medicine. He draws on insights gained from the MedSeq and BabySeq projects led by the Genomes2People Research Program (G2P).

G2P July Newsletter 2023

July 2023
G2P News

In this newsletter we’re excited to announce that the Precision Population Health initiative (PPH) is working with the South Central Foundation (SCF) on a new clinical genomic screening program to improve the health of the Alaska Native population. We are also thrilled to share that registration for the Second Annual International Conference on Newborn Sequencing … Continued

DNA sequencing in newborns reveals years of actionable findings for infants and families

Brigham and Women's Hospital |
June 2023
Press Release

“By screening apparently healthy newborns, entire families were alerted for the first time that dangerous but treatable genetic variants were present,” said corresponding author Robert C. Green, MD, MPH, a physician-scientist at Brigham and Women’s Hospital and professor of genetics at Harvard Medical School, who leads the BabySeq Project. “We were stunned to see that … Continued

The missing links: How to ensure omics data fulfills its promise

BioCentury |
May 2023

“Omics data could herald a revolution in healthcare. The analysis of rich, interconnected and longitudinal multi-omics datasets promises a better understanding of the underlying biology of human health and disease, which in turn could lead to more effective prevention, earlier and more accurate diagnoses, new treatments and better choice of treatments. Despite that promise, only … Continued

Their DNA hides a warning, but they don’t want to know what it says

The New York Times |
January 2022

The MGB Biobank returned actionable genetics results to 256 participants, 76.3 percent of whom were unaware that they carried a variant that put them at increased risk. The New York Times reports on this return of results process, outlining that some participants wanted to learn this information and others did not.

Returning genomic research findings reveals unrecognized disease risks

BWH Newsroom |
November 2021
Press Release

Press Release: In a new study published in The American Journal of Human Genetics, investigators from Brigham and Women’s Hospital, Massachusetts General Hospital and Harvard Medical School describe lessons learned from their experience disclosing actionable genetic results to research participants and transitioning them to clinical care. The team returned results to 256 participants, 76.3 percent … Continued

Diverse Boston neighborhoods recruited for sweeping study of genetics and health outcomes

GBH News |
September 2021
Press, Radio

“Medical researchers in Boston are helping sign up one million volunteers for a first-of-its-kind study [The All of Us Research Program] examining the link between genes and our health. Researchers are actively recruiting volunteers of different races and ethnicities to ensure that the study reflects the diversity of the United States.”

Sequencing every newborn’s genome to detect diseases faces ethical and practical obstacles, but the United Kingdom is pushing ahead with a major test

Science |
September 2021

Genomic testing for Baby Cora, a participant of The BabySeq Project, revealed a disorder that might otherwise have gone undetected through traditional newborn screening. “Cora’s case illustrates the promise of sequencing the entire genomes of newborns: uncovering a bounty of genetic information that could identify infants needing treatment and improve health later in life…Genomics England … Continued

G2P Newsletter July 2021

July 2021
G2P News

Our G2P research team continues to be extraordinarily productive, publishing 21 scientific papers so far this year. This summer newsletter highlights a few of these papers, as well as G2P media features, blog posts, and policy recommendations.

Combining science and service as a VA genetic counselor

VAntage Point |
March 2021

“In 2019, [G2V’s] Morgan Danowski graduated and joined Boston VA. There, she supports VA’s Million Veteran Program (MVP), now the world’s largest genomics research program. The program takes DNA from participating Veterans and information on their health, lifestyle and military experiences and exposures to better understand disease in Veteran populations. With over 830,000 Veterans enrolled, … Continued