Genomes2Veterans (G2V) Research Program

Join Us ABOUT US At G2V, we envision a future where health care uses genomics to improve human health equitably. We work towards this vision in the following ways: We conduct biomedical research to determine the role of genetic and genomic technologies in improving the care and health outcomes of Veterans and other patients. Our … Continued

Publications

2024

Development and utility of a clinical research informatics application for participant recruitment and workflow management for a return of results pilot trial in familial hypercholesterolemia in the Million Veteran Program

Brunette CA, Yi T, Danowski ME, Cardellino M, Harrison A, Assimes TL, Knowles JW, Christensen KD, Sturm AC, Sun YV, Hui Q, Pyarajan S, Shi Y, Whitbourne SB, Gaziano JM, Muralidhar S, Vassy JL

Journal of the American Medical Informatics Association Mar 2024

Processes and outcomes from a clinical genetics e-consultation service managed by a primary care physician champion

Kerman J, Zawatsky CBL, Fieg E, Frank NY, Donnelly RS, Green RC, Kennedy JC, Lakdawala Neal, Licurse AM, Perez EF, Preys CL, Krier JB, Rana HQ, Zettler B, Vassy JL

Genetics in Medicine Open Feb 2024

Helping patients understand multi-cancer early detection tests: a scoping review

Greene MP, Vassy J

Precision Medicine Jan 2024

2023

Data from a national survey of United States primary care physicians on genetic risk scores for common disease prevention

Brunette CA, Harris EJ, Antwi AA, Lemke AA, Kerman BJ, Vassy JL

Data in Brief Dec 2023

The GenoVA study: Equitable implementation of a pragmatic randomized trial of polygenic-risk scoring in primary care

Vassy JL, Brunette CA, Lebo MS, MacIsaac K, Yi T, Danowski ME, Alexander NVJ, Cardellino MP, Christensen KD, Gala M, Green RC, Harris E, Jones NE, Kerman BJ, Kraft P, Kulkarni P, Lewis ACF, Lubitz SA, Natarajan P, Antwi AA

The American Journal of Human Genetics Nov 2023

Cardiovascular disease risk assessment using traditional risk factors and polygenic risk scores in the Million Veteran Program

Vassy JL, Posner DC, Ho YL, Gagnon DR, Galloway A, Tanukonda V, Houghton SC, Madduri RK, McMahon BH, Tsao PS, Damrauer SM, O’Donnell CJ, Assimes TL, Casas JP, Gaziano JM,Pencina MJ, Sun YV, Cho K, Wilson PWF

JAMA Cardiology May 2023

Perceived benefits and barriers to implementing precision preventive care: Results of a national physician survey

Vassy JL, Kerman BJ, Harris EJ, Lemke AA, Clayman ML, Antwi AA, MacIsaac K, Yi T, Brunette CA

European Journal of Human Genetics Feb 2023

Primary care physician use of patient race and polygenic risk scores in medical decision-making

Kerman BJ, Brunette CA, Harris EJ, Antwi AA, Lemke AA, Vassy JL

Genetics in Medicine Feb 2023

Physicians and patient holding roadmap with DNA helix

Navigating the uncertainty of precision cancer screening: The role of shared decision-making

Gallagher JH, Vassy JL, Clayman ML

Patient Education and Counseling Innovation Jan 2023

2022

Performance of EHR classifiers for patient eligibility in a clinical trial of precision medicine

Alexander NVJ, Brunette CA, Guardino ET, Yi T, Kerman BJ, MacIsaac K, Harris EJ, Antwi AA, Vassy JL

Contemporary Clinical Trials Sep 2022

Effect of pharmacogenomic testing for drug-gene interactions on medication selection and remission of symptoms in major depressive disorder

Oslin DW, Lynch KG, Shih M, Ingram EP, Wray LO, Chapman SR, Kranzler HR, Gelernter J, Pyne JM, Stone A, DuVall SL, Lehmann LS, Thase ME, and the PRIME Care Research Group

JAMA Jul 2022

2021

A cost-consequence analysis of preemptive SLCO1B1 testing for statin myopathy risk compared to usual care

Brunette CA, Dong OM, Vassy JL, Danowski ME, Alexander N, Antwi AA, Christensen KD

Journal of Personalized Medicine Oct 2021

Evaluation of the Veterans Affairs Pharmacogenomic Testing for Veterans (PHASER) clinical program at initial test sites

Dong OM, Roberts MC, Wu RR, Voils CI, Sperber N, Gavin KL, Bates J, Chanfreau-Coffinier C, Naglich M, Kelley MJ, Vassy JL, Sriram P, Heise CW, Rivas S, Ribeiro M, Chapman JG, Voora D

Pharmacogenomics Oct 2021