Genomes2Veterans

As director of the Genomes2Veterans research program at the Veterans Affairs (VA) Boston Healthcare System, Jason Vassy, MD, MPH, SM, bridges the expertise of Genomes2People and the mission of bringing 21st century medical care to Veterans. Current Genomes2Veterans research projects: Integrating Pharmacogenetics in Clinical Care (I-PICC) Study Funding: U.S. Department of Veterans Affairs Office of … Continued

Publications

2022

Performance of EHR classifiers for patient eligibility in a clinical trial of precision medicine

Alexander NVJ, Brunette CA, Guardino ET, Yi T, Kerman BJ, MacIsaac K, Harris EJ, Antwi AA, Vassy JL

Contemporary Clinical Trials Sep 2022  

Effect of pharmacogenomic testing for drug-gene interactions on medication selection and remission of symptoms in major depressive disorder

Oslin DW, Lynch KG, Shih M, Ingram EP, Wray LO, Chapman SR, Kranzler HR, Gelernter J, Pyne JM, Stone A, DuVall SL, Lehmann LS, Thase ME, and the PRIME Care Research Group

JAMA Jul 2022  

2021

A cost-consequence analysis of preemptive SLCO1B1 testing for statin myopathy risk compared to usual care

Brunette CA, Dong OM, Vassy JL, Danowski ME, Alexander N, Antwi AA, Christensen KD

Journal of Personalized Medicine Oct 2021  

Evaluation of the Veterans Affairs Pharmacogenomic Testing for Veterans (PHASER) clinical program at initial test sites

Dong OM, Roberts MC, Wu RR, Voils CI, Sperber N, Gavin KL, Bates J, Chanfreau-Coffinier C, Naglich M, Kelley MJ, Vassy JL, Sriram P, Heise CW, Rivas S, Ribeiro M, Chapman JG, Voora D

Pharmacogenomics Oct 2021  

The role of SLCO1B1 genotyping in lowering cardiovascular risk

Brunette CA, Vassy JL

Pharmacogenomics Jul 2021  

2020

Effect of pharmacogenetic testing for statin myopathy risk vs usual care on blood cholesterol: A randomized clinical trial

Vassy JL, Gaziano JM, Green RC, Ferguson RE, Advani S, Miller SJ, Chun S, Hage AK, Seo S, Majahalme N, MacMullen L, Zimolzak AJ, Brunette CA

JAMA Network Open Dec 2020  

2019

Pragmatic trials in genomic medicine: The Integrating Pharmacogenetics in Clinical Care (I-PICC) study

Brunette CA, Miller SJ, Majahalme Nilla, Hau C, MacMullen L, Advani S, Ludin SA, Zimolzak AJ, Vassy JL

Clinical and Translational Science Dec 2019  

2018

The Integrating Pharmacogenetics in Clinical Care (I-PICC) Study: Protocol for a point-of-care randomized controlled trial of statin pharmacogenetics in primary care

Vassy JL, Brunette CA, Majahalme N, Advani S, MacMullen L, Hau C, Zimolzak AJ, Miller SJ

Contemporary Clinical Trials Oct 2018  

Impact of SLCO1B1 pharmacogenetic testing on patient and healthcare outcomes: A systematic review

Vassy JL, Chun S, Advani S, Ludin S, Smith J, Alligood E.

Clinical Pharmacology & Therapeutics Aug 2018  

Pharmacogenetic testing in the Veterans Health Administration (VHA): Policy recommendations from the VHA Clinical Pharmacogenetics Subcommittee

Vassy JL, Stone A, Callaghan, JT, Mendes M, Meyer LJ, Pratt VM, Przygodzki RM, Scheuner MT, Wang-Rodriguez J, Schichman SA

Genetics In Medicine Jun 2018