Sequencing every newborn’s genome to detect diseases faces ethical and practical obstacles, but the United Kingdom is pushing ahead with a major test

Science |
September 2021
Press

Genomic testing for Baby Cora, a participant of The BabySeq Project, revealed a disorder that might otherwise have gone undetected through traditional newborn screening. “Cora’s case illustrates the promise of sequencing the entire genomes of newborns: uncovering a bounty of genetic information that could identify infants needing treatment and improve health later in life…Genomics England … Continued

Low frequency of treatable pediatric disease alleles in gnomAD: An opportunity for future genomic screening of newborns

Gold NB, Harrison SM, Rowe J, Gold J, Furutani E, Biffi A, Duncan CN, Shimamura A, Lehmann LE, Green R
Human Genetics and Genomics In Press

Returning actionable genomic results in a research biobank: Analytic validity, clinical implementation and resource utilization

Zawatsky CLB, Shah N, Machini K, Perez E, Christensen KD, Zouk H, Steeves M, Koch C, Uveges M, Shea J, Gold N, Krier J, Boutin N, Mahanta L, Rehm HL, Weiss ST, Karlson EW, Smoller JW, Lebo MS, Green R,
American Journal of Human Genetics In Press

Re-evaluating the “right not to know” in genomics research

Gold NB, Green RC
Genetics in Medicine In Press

Study finds genomic sequencing of healthy newborns does not disrupt family dynamics

EurekAlert |
August 2021
Press, Press Release

“We have now shown that this information can be medically beneficial through early intervention and is not disruptive to the parent-infant relationship, and our ongoing analysis is measuring economic effects of genome sequencing. This type of research is critical to determine best practices for preventive genomic healthcare throughout the lifespan.” – Robert Green

Green receives NIH research grant for BabySeq2

Brigham Publications: Awards, Honors & Grants |
August 2021
Press

“Robert Green, MD, MPH, of the Division of Genetics, received a research grant from the National Institutes of Health (NIH) to fund The BabySeq Project: Phase II, also known as BabySeq2, the continuation of a project to study genome sequencing in newborns.”

Improved provider preparedness through an eight-part genetics and genomic education program

Galbraith LN, Hajek C, Hutchinson AM, Green RC, Murray MF, Petry N, Preys CL, Zawatsky CLB, Zoltick ES, Christensen KD
Genetics in Medicine In Press

G2P Newsletter July 2021

July 2021
G2P News

Our G2P research team continues to be extraordinarily productive, publishing 21 scientific papers so far this year. This summer newsletter highlights a few of these papers, as well as G2P media features, blog posts, and policy recommendations.

Robert Green: Newborn sequencing is the goal here in the U.S.

Mendelspod |
July 2021
Podcast

“If you go to a scientific meeting, even with the greatest critics, and you ask, how many people in this audience believe that your entire genome will be part of your everyday medical care in fifty years, every person will raise their hand. So the only questions we’re debating are: how do we get there, … Continued

Unlocking the human genetics of COVID

Medium |
July 2021
G2P Blog

In an unprecedented international effort, researchers and clinicians tackle the genomics of COVID-19 risk. In this blog post, G2P Director Robert Green writes about what we’ve learned so far concerning genetics and COVID-19 and how the G2P research program has contributed to these growing studies.

How will Aducanumab approval impact Alzheimer’s disease research?

Weiner MW, Aisen PS, Beckett LA, Green RC, Jagust William, Morris JC, Okonkwo O, Perrin RJ, Petersen RC, Mindt MR, Saykin AJ, Shaw LM, Toga AW, Trojanowski JQ and the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Journal of Prevention of Alzheimer's Disease July 2021  

Precision medicine: From breakthrough to follow-through

Medium |
May 2021
G2P Blog

Nic Encina, Director of Strategy of the Precision Population Health (PPH) Initiative at Ariadne Labs, describes the recent launch of PPH into the world of precision medicine. “We feel that Genomes2People’s real-world research in genomic return-of-results combined with Ariadne Labs’ practical approach to health system innovation and implementation are aptly suited for tackling implementation obstacles … Continued

Ariadne Labs and Genomes2People launch new Precision Population Health initiative

PR Newswire |
March 2021
Press Release

The Precision Population Health (PPH) initiative, a collaboration between Genomes2People and Ariadne Labs, aims to solve the system challenges in adopting precision medicine in primary care, and bring about a promising, equitable approach to medicine for every patient, everywhere. Our vision is not to simply introduce new tools to primary care, but rather to transform … Continued

I’m 28 and I don’t know my family history – here’s how that affects my health

Well + Good |
February 2021
Press

28 year old Mercey Livingston shares about what it means to be adopted and not know important information related to family health history and genetic health. Livingston quotes G2P’s director, Dr. Robert Green, explaining the differences between direct to consumer testing and comprehensive testing options, as well as the value of working with a genetics … Continued

NOVA “Secrets in Our DNA” screening and panel discussion

Computer History Museum |
January 2021
Video

Following a screening of the NOVA documentary, “Secrets in our DNA,” the Computer History Museum hosted a panel with science and business experts about personal genetic testing. Click the link below to hear contributions by G2P director Dr. Green.

Secrets in our DNA

NOVA |
January 2021
Video

In this NOVA documentary, G2P director Dr. Green explains what DNA can reveal about our ancestry and health, and at what risk.

Latest Med News Podcast: Episode 6 with Bethany Zettler

Latest Med News |
December 2020
Podcast

In this season finale of the Latest Med News Podcast, G2P’s Bethany Zettler shares about her work as lead genetic counselor of the Preventive Genomics Clinic and project manager of the MilSeq and BabySeq studies. Her work focuses on how genetic testing can help anyone understand their health risks and make proactive medical/lifestyle choices.